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HPLC determination of phenolic acids and antioxidant activity in concentrated peat extract — a natural immunomodulator

in-vitro Grade B 2006
Authors: Tarnawski, M., Depta, K., Grejciun, D., Szelepin, B.
Journal: Journal of Pharmaceutical and Biomedical Analysis 41 (1) : 182-188

Key Findings

  • HPLC method identified 8 phenolic acids in concentrated peat extract
  • Phenolic profiles of extracts from different medicinal peats were similar, with variations in individual acid amounts
  • Antioxidant activity evaluated by ABTS assay — differences observed between extracts from different peat varieties
  • Antioxidant activity differences reflect phenolic composition
  • Produced by Torf Corporation — Pharmaceutical Factory, Poland (TPP heritage)

First quantitative HPLC analysis of phenolic acids in concentrated peat extract. Identified 8 individual phenolic acids and measured antioxidant activity using the ABTS assay. Produced at the Torf Corporation (TPP heritage). Important because it provides the analytical chemistry behind peat’s antioxidant claims — moving from “peat has antioxidant activity” to “here are the specific compounds and their measured activity.” Listed as TIER 1 priority in papers-to-find.

phenolic-acidsantioxidantHPLCpeat-extractTPPquantificationABTS