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From in vitro research to real life studies: an extensive narrative review of the effects of balneotherapy on human immune response

review Grade B 2021
Authors: Maccarone, M., Magro, G.
Journal: Sport Sciences for Health
URL: https://consensus.app/papers/from-in-vitro-research-to-real-life-studies-an-extensive-maccarone-magro/7d5dc407c12055bebb5274387bca5e86/

Key Findings

  • Reviews effects of balneotherapy on human immune response from in-vitro to clinical
  • Documents immunomodulatory effects including T-cell and cytokine modulation
  • Bridges the gap between laboratory evidence and real-world clinical outcomes

Extensive narrative review bridging in-vitro research on balneotherapy’s effects on the immune system with real-world clinical studies. Key reference for the immunomodulatory mechanism — documents how peloid therapy modulates T-cell populations, cytokine profiles, and overall immune function. Supports the distinction between anti-inflammatory (suppression) and immunomodulatory (rebalancing) effects.

immunomodulatoryimmune-responset-cellscytokinesin-vitroclinical