Keratolytic Effects
Keratolytic activity refers to the softening and removal of the outermost layer of dead skin cells (stratum corneum). In peat, this effect is produced by the combined action of humic acids, sulfur compounds, and small organic acids, which loosen intercellular bonds and promote desquamation.
Mechanism
Humic acids soften keratin through their interaction with protein structures. Organic acids (similar to AHAs) weaken the bonds between corneocytes. Sulfur compounds break disulfide bonds in keratin. The combination produces a gentle but effective exfoliating action without the aggressive chemical peel effect of concentrated keratolytic agents.
Clinical Significance
Keratolytic effects are particularly important for conditions involving hyperkeratinization — excessive buildup of dead skin. Psoriasis plaques, dandruff flakes, and seborrheic dermatitis scales all involve abnormal keratin accumulation. Peat’s keratolytic action helps reduce this buildup while the anti-inflammatory effects address the underlying cause.
How It Works
| Targets | Keratin protein in stratum corneum |
| Pathway | Softening and dissolution of intercellular bonds in dead skin layer |