Biological Activity of Fulvic Acid: Prospects of Application in Medicine
review Grade C 2022 Language: ru Open access
Authors: Benderskiy, N.S., Safronenko, A.V., Kudelina, O.M., Gantsgorn, E.V., Krishtopa, A.V., Golubeva, A.O., Babyuk, S.E.
Journal: Journal Biomed (Биомедицина) 18 (3) : 79-83
Key Findings
- Fulvic acid anti-inflammatory and antiallergic properties relevant to eczema and bronchial asthma
- FA promotes overexpression of IL-10 (anti-inflammatory cytokine) accelerating wound healing
- Carbohydrate-derived fulvic acid demonstrated safe compound with anti-inflammatory and wound healing properties in rats
- FA antioxidant activity attributed to oxygen reactive binding capacity
- FA promotes Nrf2 transcription factor function and its coding proteins for wound healing via oxidative stress protection
Russian-language review summarizing fulvic acid’s pharmacological effects and medical applications. Covers anti-inflammatory, antiallergic, and antioxidant properties with emphasis on wound healing mechanisms. Highlights carbohydrate-derived FA’s role in IL-10 overexpression and Nrf2 pathway activation. Concludes that FA is a promising pharmacological agent but insufficient evidence exists for standalone medical use — currently used experimentally as adjunct to standard therapy.
fulvic-acidanti-inflammatoryantiallergicantioxidantwound-healingreview